Feline Morbillivirus - A Newly Reported Cause Of Interstitial Nephritis In Cats

Discussion in 'Veterinary News' started by Admin, Jun 25, 2016.

By Admin on Jun 25, 2016 at 8:19 AM
  1. Admin

    Admin Administrator Staff Member

    Courtesy of Vetbook.org

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    Morbillivirus

    The Morbillivirus is a paramyxovirus viral disease which has been reported in cats recently[1] from samples taken from urine, rectum and blood in cats from Hong Kong and Japan[2].

    Diagnosis of virus is based on PCR testing allied with clinical signs.

    Clinical signs are usually associated with tubular interstitial nephritis, with vomiting and diarrhoea commonly seen initially.

    Pathological changes noted during histopathological examination of affected cats revealed interstitial inflammatory infiltrate and tubular degeneration/necrosis in kidneys, with decreased cauxin expression in degenerated tubular epithelial cells.

    Supportive treatment (IV fluids) is recommended at this stage.



    References
    1. Jump up↑ Woo, PC et al (2012) Feline morbillivirus, a previously undescribed paramyxovirus associated with tubulointerstitial nephritis in domestic cats. http://www.pnas.org/content/suppl/2012/03/13/1119972109.DCSupplemental
    2. Jump up↑ Park ES et al (2014) Identification of a natural recombination in the F and H genes of feline morbillivirus. Virology 468-470C:524-531
     

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Discussion in 'Veterinary News' started by Admin, Jun 25, 2016.

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